Title of article :
Heronamycin A: a new benzothiazine ansamycin from an Australian marine-derived Streptomyces sp.
Author/Authors :
Raju، نويسنده , , Ritesh and Piggott، نويسنده , , Andrew M. and Khalil، نويسنده , , Zeinab and Bernhardt، نويسنده , , Paul V. and Capon، نويسنده , , Robert J.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Chemical analysis of a marine-derived Streptomyces sp. (CMB-M0392) isolated from sediment collected off Heron Island, Queensland, Australia, yielded a new benzothiazine ansamycin, heronamycin A. The absolute stereostructure of heronamycin A was determined by detailed spectroscopic analysis and X-ray crystallography. Heronamycin A exhibited modest antimicrobial activity against Bacillus subtilis strains ATCC 6051 and 6633 (IC50 = 18 and 14 μM, respectively).
Keywords :
herbimycin A , Natural products chemistry , Marine-derived Streptomyces , Benzothiazine ansamycin
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
