• Title of article

    An efficient regioselective synthesis of highly functionalized 3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidines via an isocyanide-based three-component reaction

  • Author/Authors

    Esmaeili، نويسنده , , Abbas Ali and Zangouei، نويسنده , , Mahdieh and Fakhari، نويسنده , , Ali Reza and Habibi، نويسنده , , Azizollah، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2012
  • Pages
    3
  • From page
    1351
  • To page
    1353
  • Abstract
    We present a novel, convenient, and efficient method for synthesizing polysubstituted 3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidines via a three-component reaction. The zwitterions generated from the reaction of isocyanides and dialkyl acetylenedicarboxylates react with 2-imino-1,3-thiazolidin-4-one to produce the title compounds in good yields.
  • Keywords
    3-Thiazolidin-4-one , 2-a]pyrimidine , 2-Imino-1
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2012
  • Journal title
    Tetrahedron Letters
  • Record number

    1880259