• Title of article

    1,2-Dimethoxy-4,5-dimethylene: a new protecting group for acyclic amino acid derivatives prepared by Stevens rearrangement

  • Author/Authors

    Tayama، نويسنده , , Eiji and Takedachi، نويسنده , , Keisuke S. Iwamoto، نويسنده , , Hajime and Hasegawa، نويسنده , , Eietsu، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2012
  • Pages
    3
  • From page
    1373
  • To page
    1375
  • Abstract
    A new protecting group, 1,2-dimethoxy-4,5-dimethylene, for acyclic amino acid derivatives could be introduced by N,N-dialkylation with 1,2-bis(bromomethyl)-4,5-dimethoxybenzene (1) and removed via amine de-alkylation with acyl chlorides. The method can be used with base-induced [2,3] and [1,2] Stevens rearrangement products.
  • Keywords
    Amino acid , Ammonium salt , Ylide , Rearrangement , PROTECTION
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2012
  • Journal title
    Tetrahedron Letters
  • Record number

    1880265