Title of article
Synthesis of carbohydrate-functionalized thiophene-capped cyclopenta[c]thiophene for concanavalin A recognition
Author/Authors
Das، نويسنده , , Soumyajit and Mandal، نويسنده , , Santanu and Mukhopadhyay، نويسنده , , Balaram and Zade، نويسنده , , Sanjio S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
1464
To page
1467
Abstract
Synthetic route to two different carbohydrate-functionalized oligothiophenes comprising central cyclopenta[c]thiophene (CPT) moiety was demonstrated. Turbidimetric analysis revealed enhanced interaction for divalent α-mannose-functionalized terthiophene 7 with Con A. The extent of binding interaction for 7-Con A complex formation was determined from isothermal titration calorimetry (ITC) measurements and the binding constant found (KITC) 2.4(6) × 105 M−1.
Keywords
Oligothiophene , Concanavalin A , carbohydrate
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880288
Link To Document