Author/Authors :
Francuz، نويسنده , , Jovana and Sre?o، نويسنده , , Bojana and Popsavin، نويسنده , , Mirjana and Benedekovi?، نويسنده , , Goran and Divjakovi?، نويسنده , , Vladimir and Koji?، نويسنده , , Vesna and Bogdanovi?، نويسنده , , Gordana and Kapor، نويسنده , , Agne? and Popsavin، نويسنده , , Velimir، نويسنده ,
Abstract :
Treatment of 7-O-benzoyl-5-O-benzyl derivatives of (+)-goniofufurone or 7-epi-(+)-goniofufurone with titanium(IV) chloride or titanium(IV) bromide gave 7-chloro and 7-bromo-7-deoxy-goniofufurone mimics as the main reaction products along with minor amounts of the corresponding C-7 epimers. An unexpected cyclized product, benzoxepane 8 was isolated in some cases.
Keywords :
7-epi-Goniofufurone mimics , antitumour agents , Titanium(IV)-mediated halogenation , styryl lactones , Goniofufurone mimics
