Title of article
Modular synthesis of photocleavable peptides using click chemistry
Author/Authors
Baccile، نويسنده , , Joshua A. and Morrell، نويسنده , , Mark A. and Falotico، نويسنده , , Ross M. and Milliken، نويسنده , , Brandon T. and Drew، نويسنده , , Daniel L. and Rossi، نويسنده , , Francis M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
1933
To page
1935
Abstract
A modular synthesis of photocleavable peptides was developed. Peptide based kinase substrates were modified on solid support with a traceless linker derived from 1-(2-nitrophenyl)propargyl alcohol and coupled to azide functionalized cell-penetrating peptides using Cu(I) catalyzed click chemistry.
Keywords
click chemistry , caged compounds , Cell-penetrating peptides , Photocleavable linkers
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880482
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