Title of article
Stereoselective synthesis of a dialkylhydantoin featuring an asymmetric Strecker reaction on an acyclic dialkyl ketone
Author/Authors
Barnwell، نويسنده , , Neil and Watts، نويسنده , , Andrew and Purdie، نويسنده , , Lindsay and Gill، نويسنده , , Duncan M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
1951
To page
1953
Abstract
A diastereoselective Strecker reaction using (R)-(−)-phenylglycinol forms the basis of a concise scalemic route to dialkylhydantoin 1. The phenylglycinol functionality was exploited in the manipulation of the aminonitrile Strecker product through to the dialkylhydantoin via a short, efficient sequence involving crystalline intermediates.
Keywords
asymmetric , Hydantoin , stereoselective synthesis , Strecker reaction
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880489
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