Title of article
Chelation controlled reductive amination of cyclic ketones to trans-4-methoxycyclohexylamines: 9-BBN reduction mediated with FeCl3
Author/Authors
Qu، نويسنده , , Bo and Haddad، نويسنده , , Nizar and Rodriguez، نويسنده , , Sonia and Lee، نويسنده , , Heewon and Ma، نويسنده , , Shengli and Zeng، نويسنده , , Xingzhong and Reeves، نويسنده , , Diana C. and Sidhu، نويسنده , , Kanwar P.S. and Lorenz، نويسنده , , Jon C. and Grinberg، نويسنده , , Nelu and Busacca، نويسنده , , Carl A. and Krishnamurthy، نويسنده , , Dhileepkumar and Senanayake، نويسنده , , Chris ، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
1982
To page
1986
Abstract
A novel trans-diastereoselective reductive amination of 4-substituted cyclohexanones is described using 9-BBN as reducing agent in the presence of FeCl3. The method permits efficient synthesis of structurally diverse 4-trans-alkoxycyclohexylamines.
Keywords
diastereoselective , 9-BBN , FeCl3 , chelation , reductive amination
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880507
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