Author/Authors :
He، نويسنده , , Fei and Liu، نويسنده , , Zhong and Yang، نويسنده , , Jing-Li Fu ، نويسنده , , Peng and Peng، نويسنده , , Jiang and Zhu، نويسنده , , Weiming and Qi، نويسنده , , Shu-Hua، نويسنده ,
Abstract :
Penispirolloid A (1), a novel alkaloid possessing a unique spiro imidazolidinyl skeleton, was isolated from a halotolerant fungal strain, Penicillium sp. OUCMDZ-776. Its structure was elucidated on the basis of spectroscopic methods and quantum chemical CD calculation. Compound 1 showed significant antifouling activity toward Bugula neritina larvae with EC50 of 2.40 μg/ml. Plausible biogenesis of compound 1 was also proposed.
