Title of article :
Synthesis of novel dispiro-oxindoles via 1,3-dipolar cycloaddition reactions of azomethine ylides
Author/Authors :
Al Mamari، نويسنده , , Khalil and Ennajih، نويسنده , , Hamid and Zouihri، نويسنده , , Hafid and Bouhfid، نويسنده , , Rachid and Ng، نويسنده , , Seik Weng and Essassi، نويسنده , , El Mokhtar، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
The 1,3-dipolar cycloaddition of 1-allyl-5-haloisatin derivatives as dipolarophiles with the azomethine ylides generated in situ from N-allylisatin and l-proline to furnish novel dispiro-oxindoles has been investigated. The structures and relative stereochemistry of both types of cycloadducts were confirmed by single crystal X-ray diffraction, 1H and 13C NMR spectroscopy and mass spectrometry.
Keywords :
L-proline , 1 , Azomethine ylide , 3-dipolar cycloaddition , X-ray diffraction , Isatin
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
