Title of article
Solvent free, N,N′-carbonyldiimidazole (CDI) mediated amidation
Author/Authors
Verma، نويسنده , , Sanjeev K. and Ghorpade، نويسنده , , Ramarao and Pratap، نويسنده , , Ajay and Kaushik، نويسنده , , M.P.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
2373
To page
2376
Abstract
The method involves CDI mediated amidation under solvent-free conditions. The protocol is green, simple, and scalable and has broad structural applicability. The protocol has also been used for BOC protection of amine. The protocol has reduced the time for CDI mediated amidation from 2–4 h to 5–10 min without the use of any dry organic solvent and nitrogen atmosphere.
Keywords
Boc protection , green chemistry , CDI , Amidation
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880661
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