Title of article :
Solvent free, N,N′-carbonyldiimidazole (CDI) mediated amidation
Author/Authors :
Verma، نويسنده , , Sanjeev K. and Ghorpade، نويسنده , , Ramarao and Pratap، نويسنده , , Ajay and Kaushik، نويسنده , , M.P.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
The method involves CDI mediated amidation under solvent-free conditions. The protocol is green, simple, and scalable and has broad structural applicability. The protocol has also been used for BOC protection of amine. The protocol has reduced the time for CDI mediated amidation from 2–4 h to 5–10 min without the use of any dry organic solvent and nitrogen atmosphere.
Keywords :
Boc protection , green chemistry , CDI , Amidation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
