Title of article
Gallium(III)-catalyzed tandem cycloisomerization/Friedel–Crafts alkylation: a facile synthesis of 2,5-disubstituted furans
Author/Authors
Reddy، نويسنده , , B.V. Subba and Bramha Reddy، نويسنده , , B. and Raghavendra Rao، نويسنده , , K.V. and Yadav، نويسنده , , J.S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
2500
To page
2503
Abstract
A tandem cycloisomerization/Friedel–Crafts alkylation of indoles has been achieved in a one-pot process to produce 2,5-disubstituted furans using gallium-catalyzed sequential nucleophilic addition onto metal-activated 1-alkynyl-2,3-epoxy acetates. The reaction proceeds efficiently under mild conditions with complete regioselectivity to afford the substituted furan derivatives in good yields with high diversity.
Keywords
1-Alkynyl-2 , Gallium(III) chloride , 3-epoxy acetates , 2 , 5-Disubstituted furans , Friedel–Crafts alkylation
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880717
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