Author/Authors :
Chris Limberakis، نويسنده , , Chris and Li، نويسنده , , Jianke and Balan، نويسنده , , Gayatri and Griffith، نويسنده , , David A. and Kung، نويسنده , , Daniel W. and Rose، نويسنده , , Colin and Vrieze، نويسنده , , Derek، نويسنده ,
Abstract :
Complementary α-alkylation methods are used to derivatize a sterically hindered spiro[pyrazolopyranpiperidine]ketone. More specifically, enolate alkylations in the presence of DMPU and aldol condensations are employed to deliver these compounds.
Keywords :
4-addition , DMPU , Enolate alkylation , 1 , Aldol condensation
