Synthesis of new C-glycosyl aza-β3-amino acids building blocks

New C-glycosylated Nβ-protected aza-β3-amino acid building blocks have been prepared from C-glycosyl aldehydes of gluco and galacto configuration by reductive amination and subsequent N-alkylation. These moieties were elaborated to β-dipeptides by elongation at the C- or the N-terminus establishing their ability to be incorporated in original glycosylated foldamers.