Title of article :
Tetrahydroquinazoline-substituted chromones from Diels–Alder reaction of (E)-2-styrylchromones and pyrimidine ortho-quinodimethane
Author/Authors :
Patoilo، نويسنده , , Diana T. and Silva، نويسنده , , Artur M.S. and Pinto، نويسنده , , Diana C.G.A. and Santos، نويسنده , , Clementina M.M. and Tomé، نويسنده , , Augusto C. and Cavaleiro، نويسنده , , José A.S.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
The Diels–Alder reaction of (E)-2-styrylchromones with a pyrimidine ortho-quinodimethane is reported for the first time. These cycloaddition reactions afford mixtures of two regioisomeric tetrahydroquinazoline-substituted chromones in moderate to excellent global yields. Irrespective of the substituents on the 2-styrylchromones, the 2-(7-aryl-4-methoxy-2-methyl-5,6,7,8-tetrahydroquinazolin-6-yl)chromone derivatives are always the major isomers.
Keywords :
Tetrahydroquinazolines , Cycloadditions , 2-Styrylchromones , Pyrimidine ortho-quinodimethane , NMR
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
