Title of article
Katorazone, a new yellow pigment with a 2-azaquinone-phenylhydrazone structure produced by Streptomyces sp. IFM 11299
Author/Authors
Abdelfattah ، نويسنده , , Mohamed S. and Toume، نويسنده , , Kazufumi and Arai، نويسنده , , Midori A. and Masu، نويسنده , , Hyuma and Ishibashi، نويسنده , , Masami، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
3346
To page
3348
Abstract
An unusual alkaloid with a 2-azaquinone-phenylhydrazone structure, katorazone (1), and other metabolites were isolated from the ethyl acetate extract of Streptomyces sp. IFM 11299. The chemical structure of katorazone (1) was elucidated by 1D and 2D NMR analyses together with HR-ESI mass spectrometry. Katorazone (1) showed a synergistic effect in combination with TRAIL and decreased the viability of human gastric adenocarcinoma (AGS) cells.
Keywords
Phenylhydrazone , Streptomyces , Azaquinone
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881062
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