Title of article
A tandem olefin migration and Prins cyclization using Cu(OTf)2–bisphosphine complexes: an improved synthesis of functionalized tetrahydropyrans
Author/Authors
Ghosh، نويسنده , , Arun K. and Nicponski، نويسنده , , Daniel R. and Kass، نويسنده , , Jorden، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
3699
To page
3702
Abstract
In situ-generated (bis-DPPMB)–Cu(OTf)2 complex has been examined to catalyze a tandem olefin migration and Prins cyclization of an alkenol with various aldehydes. The reaction proceeded with electron-rich aromatic aldehydes at room temperature and provided functionalized tetrahydropyrans in good yields. An efficient synthesis of the bis-DPPMB ligand has also been described.
Keywords
Phosphine ligand , Prins cyclization , Phosphine–borane adduct , tetrahydropyrans , Prins chemistry
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881215
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