Title of article
First stereoselective total synthesis of Phomolide G and H via RCM protocol
Author/Authors
Ramesh، نويسنده , , Palakuri and Chennakesava Reddy، نويسنده , , B. and Meshram، نويسنده , , H.M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
3735
To page
3738
Abstract
A first total synthetic route has been reported for the synthesis of Phomolide G and H. The syntheses of fragments were initiated from commercially available and inexpensive starting material (R)-epichlorohydrin. The synthesis involves a key Sharpless epoxidation, stereoselective epoxide opening, lactonization and ring closing metathesis (RCM).
Keywords
Lactonization , Ring closing metathesis (RCM) , Grubb’s catalyst , (R)-Epichlorohydrin , epoxidation
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881231
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