Title of article
Highly enantioselective Michael addition of cyclic ketones to chalcones catalyzed by pyrrolidine-based imides
Author/Authors
Xie، نويسنده , , Hong-Yu and Ban، نويسنده , , Shu-Rong and Liu، نويسنده , , Ju-Na and Li، نويسنده , , Qing-Shan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
3865
To page
3868
Abstract
An efficient procedure for asymmetric Michael addition reaction of cyclic ketones with low activated chalcones catalyzed by pyrrolidine-based phthalimide and 1,8-Naphthalimide catalysts was developed. The corresponding products were obtained in high yields with high diastereoselectivities (up to 99:1 dr) and high enantioselectivities (up to 96% ee) under mild conditions.
Keywords
Chalcones , enantioselective , Michael addition , cyclic ketones
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881290
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