Title of article
Sinulasulfoxide and sinulasulfone, sulfur-containing alkaloids from the Indonesian soft coral Sinularia sp.
Author/Authors
Putra، نويسنده , , Masteria Yunovilsa and Ianaro، نويسنده , , Angela and Panza، نويسنده , , Elisabetta and Bavestrello، نويسنده , , Giorgio and Cerrano، نويسنده , , Carlo and Fattorusso، نويسنده , , Ernesto and Taglialatela-Scafati، نويسنده , , Orazio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
3937
To page
3939
Abstract
Chemical analysis of the Indonesian soft coral Sinularia sp. (order Alcyonacea, family Alcyoniidae) afforded two new alkaloids, named sinulasulfoxide (1) and sinulasulfone (2), characterized by an amide linkage between a phytanic acid moiety and an uncommon sulfur-containing unit. Their complete stereostructures were elucidated by interpretation of MS and NMR data along with CD analysis and chemical modifications. Sinulasulfoxide (1) proved to moderately inhibit LPS-induced NO release.
Keywords
Sulfur-containing compounds , Sinularia , Alkaloids , iNOS inhibition , Soft coral
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881321
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