Title of article
Synthesis of 5-alkynylated uracil–morpholino monomers using Sonogashira coupling
Author/Authors
Paul، نويسنده , , Sibasish and Nandi، نويسنده , , Bappaditya and Pattanayak، نويسنده , , Sankha and Sinha، نويسنده , , Surajit، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
4179
To page
4183
Abstract
Sonogashira coupling of 5-iodo uracil–morpholino monomer with different terminal alkynes has been achieved for first time in good to excellent yields (67–86%). We have optimized the iodination conditions for the preparation of 5-iodo uracil–morpholino monomer under basic condition.
Keywords
Uracil–morpholino , iodination , detritylation , Sonogashira coupling , Alkynyl-derivatives
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881446
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