Title of article
Copper catalysed domino decarboxylative cross coupling-cyclisation reactions: synthesis of 2-arylindoles
Author/Authors
Ponpandian، نويسنده , , Thanasekaran and Muthusubramanian، نويسنده , , Shanmugam، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
4248
To page
4252
Abstract
The efficient synthesis of 2-arylindoles and 6H-isoindolo[2,1-a]indol-6-one through copper catalysed domino sp-sp2 decarboxylative cross-coupling and subsequent cyclisation reactions of arylpropiolic acids with 2-iodotrifluoroacetanilide has been described. This methodology also demonstrates that indolo[1,2-c]quinazolin-6(5H)-one can be obtained with the elimination of trifluoromethyl anion.
Keywords
Copper mediated reactions , Decarboxylative cross-coupling , Domino reaction , 2-Alkynoic acid , 2-Iodotrifluoroacetanilide
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881483
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