Title of article
Synthesis of 1-aminopyrrolizidine alkaloid (−)-absouline by stereoselective aminoconjugate addition
Author/Authors
Eklund، نويسنده , , Emily J. and Pike، نويسنده , , Robert D. and Scheerer، نويسنده , , Jonathan R.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
4644
To page
4647
Abstract
The diastereoselective aminoconjugate addition of benzylamine and lithiobenzylamine to both E and Z-configured vinylogous proline derivatives has been investigated. The results from this study have enabled the stereoselective synthesis of the 1-aminopyrrolizidine alkaloid (−)-absouline.
Keywords
Pyrrolizidine alkaloids , Horner–Wadsworth–Emmons olefination , Alkaloid synthesis , Heteroconjugate addition , (?)-Absouline
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881639
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