Title of article
Highly enantioselective hydrogenation of new 2-functionalized quinoline derivatives
Author/Authors
Maj، نويسنده , , Anna M. and Suisse، نويسنده , , Isabelle and Méliet، نويسنده , , Catherine and Hardouin، نويسنده , , Christophe and Agbossou-Niedercorn، نويسنده , , Francine، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
4747
To page
4750
Abstract
The asymmetric hydrogenation of a new series of 2-functionalized quinolines has been developed in the presence of in situ generated catalysts obtained from [Ir(cod)Cl]2/(R)-bisphosphine/I2 combinations. The enantioselectivity levels were as high as 84–94% ee for the synthesis of 1,2,3,4-tetrahydroquinolines.
Keywords
Asymmetric catalysis , iridium , Quinolines , Hydrogenation
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881686
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