Title of article
A convenient one-pot synthesis of ethylene blue
Author/Authors
Cody، نويسنده , , Jeremy A. and Larrabee، نويسنده , , Christian S. and Clark، نويسنده , , Michael D. and Hlynchuk، نويسنده , , Sofiya and Tatum، نويسنده , , Jacob A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
4896
To page
4899
Abstract
We have developed an efficient one-pot, two-step preparation of ethylene blue by eliminating aqueous work-ups and cumbersome purification techniques. Our procedure generates ethylene blue in good overall yields of 45–56% with approximately 95% purity, which is uncommon for the synthesis of a phenothiazinium salt. Due to its unique properties, ethylene blue has great potential for a broad range of biological applications and, as a result, an efficient procedure for the synthesis of ethylene blue is critical.
Keywords
Synthesis , One-pot , Dye , Phenothiazinium , Ethylene blue
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881743
Link To Document