Title of article
Synthesis of novel chiral monophosphine ligands derived from isomannide and isosorbide. Application to enantioselective hydrogenation of olefins
Author/Authors
Ibrahim، نويسنده , , Houssein and Bournaud، نويسنده , , Chloée and Guillot، نويسنده , , Régis and Toffano، نويسنده , , Martial and Vo-Thanh، نويسنده , , Giang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
4900
To page
4902
Abstract
A new class of monophosphine ligands has been prepared from natural chirality renewable source, 1,4:3,6-dianhydrohexitol compounds, via a nucleophilic substitution process, or a hydrophosphination reaction involving microwave activation. These ligands have been evaluated for the rhodium-catalyzed enantioselective hydrogenation of olefins giving good conversion and enantioselectivity up to 95% and 96% ee, respectively.
Keywords
Monophosphine ligands , Hydrogenation , isosorbide , Isomannide
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881746
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