Author/Authors :
Jeserich، نويسنده , , Michael E. Pape، نويسنده , , Linda and Just، نويسنده , , Hanjِrg and Hornig، نويسنده , , Burkhard and Kupfer، نويسنده , , Martin and Münzel، نويسنده , , Thomas P. Lohmann، نويسنده , , Antje and Olschewski، نويسنده , , Manfred and Drexler، نويسنده , , Helmut، نويسنده ,
Abstract :
The present study demonstrates that peripheral vasodilatory capacity is impaired in patients with chronic congestive heart failure not treated with aspirin, but preserved in patients taking aspirin. This decreased peripheral vasodilatory capacity can be restored by chronic angiotensin-converting enzyme inhibition, indicating that locally acting cyclooxygenase-dependent factors contribute to peripheral vasoconstriction in chronic congestive heart failure.
