Title of article :
Preparation of enol ester epoxides and their ring-opening to α-silyloxyaldehydes
Author/Authors :
Gregory K. Friestad، نويسنده , , Gregory K. and Sreenilayam، نويسنده , , Gopeekrishnan and Cannistra، نويسنده , , Joseph C. and Slominski، نويسنده , , Luke M.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
The Z-selective ruthenium-catalyzed addition of aromatic carboxylic acids to alkynes was followed by dioxirane epoxidation to furnish enol ester epoxides with cis configuration. Upon treatment of enol ester epoxides with tert-butyldimethylsilyl triflate in the presence of 2,6-lutidine, synthetically useful α-silyloxyaldehydes were obtained. This novel transformation was facilitated by microwave irradiation.
Keywords :
Enol esters , epoxides , Oxidation , Aldehydes
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
