Title of article
Titanium-mediated cross-coupling reactions of imines with ketones or aldehydes: an efficient route for the synthesis of 1,2-amino alcohols
Author/Authors
Fan، نويسنده , , Guoqin and Liu، نويسنده , , Yuanhong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
5084
To page
5087
Abstract
The cross-coupling reactions of imines with ketones using Ti(OiPr)4/c-C5H9MgCl reagent lead to 1,2-amino alcohols after hydrolysis. The coupling reactions with aldehydes could also afford 1,2-amino alcohols, however, in some cases, aziridines were obtained as major products in a stereoselective manner.
Keywords
Titanium-imine complex , Azatitanacyclopropane , Coupling , Ketones and aldehydes , 1 , 2-Amino alcohol
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881958
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