Author/Authors :
Maj، نويسنده , , Jadwiga and Morzycki، نويسنده , , Jacek W. and Rلrovل، نويسنده , , Lucie and Wasilewski، نويسنده , , Grzegorz and Wojtkielewicz، نويسنده , , Agnieszka، نويسنده ,
Abstract :
Two aromatic retinoids were synthesized from styrene derivatives using a novel strategy with a cross-metathesis reaction as a key step. The biological activity of the new etretinate analogues was tested. Cross-metathesis reactions were also employed for the preparation of ethyl retinoate and its 9Z-isomer via the C15 + C5 route.
Keywords :
Retinoids , cross-metathesis , Etretinate analogues , Polyenes
