Title of article :
T3P®-DMSO mediated one pot cascade protocol for the synthesis of 4-thiazolidinones from alcohols
Author/Authors :
Sharath Kumar C.، نويسنده , , Kothanahally S. and Swaroop، نويسنده , , Toreshettahally R. and Harsha، نويسنده , , Kachigere B. and Narasimhamurthy، نويسنده , , Kereyagalahally H. and Rangappa، نويسنده , , Kanchugarakoppal S. Rangappa، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Propylphosphonic anhydride (T3P®)-DMSO mediated oxidation of alcohols to carbonyl compounds and their subsequent cyclization with aryl/hetero aryl amines and thioglycolic acid to afford 4-thiazolidinones has been reported. Synthesis of 4-thiazolidinones directly from alcohols has been carried out for the first time. Mild reaction conditions, wide functional group tolerance, ease of work-up, and good yields are the noteworthy features of this protocol.
Keywords :
Propylphosphonic anhydride (T3P®) , Cascade , 4-Thiazolidinones , Thioglycolic acid (or mercaptoacetic acid)
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
