Title of article
Preparation of azidoaryl- and azidoalkyloxazoles for click chemistry
Author/Authors
Loner، نويسنده , , Catherine M. and Luzzio، نويسنده , , Frederick A. and Demuth، نويسنده , , Donald R.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
5641
To page
5644
Abstract
A series of azidoaryl- and azidoalkyl(diphenyl)oxazole scaffolds were warranted for biofilm inhibition studies. Cyclization of azidoaryl- or azidoalkyl esters of benzoin with ammonium acetate in acetic acid gives 2-azidoaryl- or 2-azidoalkyl-4,5-diphenyloxazoles. The azidoaryl esters are prepared from the corresponding azidocarboxylic acids/acid chlorides while the azidoalkyl esters are prepared from the corresponding haloalkyl esters.
Keywords
oxazoles , Biofilms , Peptidomimetics , Azides , click chemistry
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1882313
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