Title of article :
One-pot synthesis of 4(3H)-quinazolinones from azides, alkynes, anilines, and carbon monoxide
Author/Authors :
Shen، نويسنده , , Yang and Han، نويسنده , , Chao and Cai، نويسنده , , Shuying and Lu، نويسنده , , Ping and Wang، نويسنده , , Yanguang، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
A one-pot synthesis of 4(3H)-quinazolinones from terminal alkynes, sulphonyl azide, o-iodoanilines, and carbon monoxide has been developed. This cascade process includes the copper-catalyzed three-component reaction of alkyne, azide and amine, the palladium-catalyzed carbonylation, and the Lewis acid catalyzed hydrolysis of sulfonamide.
Keywords :
cascade reactions , carbonylation , Quinazolinones , Ketenimines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
