Author/Authors :
Wang، نويسنده , , Wei and Chen، نويسنده , , Ke and Qu، نويسنده , , Dezhong and Chi، نويسنده , , Weilin and Xiong، نويسنده , , Wei and Huang، نويسنده , , Yanxiang and Wen، نويسنده , , Jian and Feng، نويسنده , , Shipeng and Zhang، نويسنده , , Biliang، نويسنده ,
Abstract :
A convenient, one step conjugation method based on click chemistry has been developed for creating new RNA conjugates. The coupling reaction was performed in RNA 2′-hydroxy deprotection solution, with conjugation and TBDMS-deprotection being accomplished at the same time.
Keywords :
click chemistry , RNA labeling , RNA modification , Small-molecule-RNA conjugation
