Title of article :
A novel approach for highly regio- and stereoselective synthesis of (Z)-3-methyleneisoindoline-1-ones in aqueous micellar medium
Author/Authors :
Sarkar، نويسنده , , Swarbhanu and Dutta، نويسنده , , Samrat and Dey، نويسنده , , Rajdip and Naskar، نويسنده , , Subhendu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Pages :
4
From page :
6789
To page :
6792
Abstract :
An environmentally benign and operationally simple methodology was developed for the regio- and stereoselective synthesis of (Z)-3-methyleneisoindolinones in aqueous micellar medium from 2-iodo-N-phenyl-benzamides and terminal alkyne by Cu-free domino Sonogashira reaction followed by 5-exo-dig-cyclization using Pd(CH3CN)Cl2 as catalyst and 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene as ligand under aerobic condition.
Keywords :
(Z)-3-Methyleneisoindoline-1-one , Cu-free Sonogashira , Micelle , 5-Exo-dig cyclization , reaction in water
Journal title :
Tetrahedron Letters
Serial Year :
2012
Journal title :
Tetrahedron Letters
Record number :
1882944
Link To Document :
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