Title of article
Organocatalytic synthesis of novel purine and pyrimidine acyclic nucleosides
Author/Authors
Palazzolo، نويسنده , , Martيn A. and Pérez-Sلnchez، نويسنده , , Marيa and Iribarren، نويسنده , , Adolfo M. and Lewkowicz، نويسنده , , Elizabeth S. and Domيnguez de Marيa، نويسنده , , Pablo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
6797
To page
6800
Abstract
Organocatalysis is assessed for the first time in the synthesis of purine and pyrimidine acyclic nucleosides providing high yields and straightforward work-up procedures. Nucleobases containing aldehydes are catalytically ligated (C–C bond formation) to acetone or to phosphonate-containing ketones by means of pyrrolidine or silica-immobilized piperazine as amine-based organocatalysts.
Keywords
Piperazine , acyclic nucleosides , organocatalysis , pyrrolidine , Phosphonate
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1882950
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