Title of article :
A novel and efficient synthesis of 3,3-disubstituted indol-2-ones via Passerini three-component reactions in the presence of 4 إ molecular sieves
Author/Authors :
Esmaeili، نويسنده , , Abbas Ali and Amini Ghalandarabad، نويسنده , , Saeid and Jannati، نويسنده , , Saeideh، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The Passerini coupling of cyclohexylisocyanide with isatins and carboxylic acids in the presence of 4 إ molecular sieves is described. This process offers a highly efficient and atom-economic access to 3-acyloxy-3-carboxamido-1,3-dihydro-2H-indol-2-ones in high to excellent yields.
Keywords :
Passerini coupling reaction , 3 , isocyanide , 3-Disubstituted indol-2-ones , Isatin , Carboxylic acid
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
