Author/Authors :
Gillis، نويسنده , , Anne M. and Wyse، نويسنده , , George and Mitchell، نويسنده , , L.Brent and Duff، نويسنده , , Henry J.، نويسنده ,
Abstract :
The myocardium accumulation and pharmacodynamics of propafenone were evaluated during intravenous infusion in 6 patients undergoing electrophysiologic study for evaluation of ventricular tachycardia. The myocardial accumulation of propafenone was delayed and resulted in nonlinear arterial concentration-effect relations.