Author/Authors :
Raju، نويسنده , , Ritesh and Gromyko، نويسنده , , Oleksandr and Fedorenko، نويسنده , , Viktor and Herrmann، نويسنده , , Jennifer and Luzhetskyy، نويسنده , , Andriy and Müller، نويسنده , , Rolf، نويسنده ,
Abstract :
Chemical analysis of a terrestrial actinomycete (Lv-6-8) isolated from the root zone of Yucca aloiofolia yielded a new anthraquinone possessing a 3-furanone ring system, rubimycinone A (1). The structure of 1 was elucidated based on spectroscopic methods including UV, HR-ESIMS and 1D, and 2D NMR data. Rubimycinone A (1) displayed modest to good antibacterial and cytotoxic activity against a panel of Gram positive strains and various cancer cell lines.
