Author/Authors :
Viana، نويسنده , , Gil Mendes and de Sequeira Aguiar، نويسنده , , Lْcia Cruz and de Araْjo Ferrمo، نويسنده , , Jonas and Simas، نويسنده , , Alessandro Bolis Costa and Vasconcelos، نويسنده , , Marcela Guariento، نويسنده ,
Abstract :
We report a straightforward and efficient reaction protocol for the syntheses of substituted ureas via treatment of thioureas with aqueous potassium dichloroiodate (KICl2). By tuning the reaction condition, thioureas bearing activated N-aryl substituents may undergo either selective oxidation or sequential oxidation and iodination, forming iodoaryl ureas in the latter case.
Keywords :
Ureas , Potassium dichloroiodate , Oxidation , Halogenation
