Regio- and stereoselective preparation of (Z)-silyl enol ethers by three-component coupling using α,β-unsaturated acylsilanes as core building blocks

Based on the conjugate addition–silyl migration–alkylation strategy, (Z)-silyl enol ethers possessing a stereocenter at the γ-position were prepared with complete regio- and stereoselectivity by three-component coupling of α,β-unsaturated acylsilanes, Grignard reagents (or cuprates)/copper(I) tert-butoxide, and organic halides.