Author/Authors :
Suzuki، نويسنده , , Eriko and Ueda، نويسنده , , Minoru and Ohba، نويسنده , , Shigeru and Sugai، نويسنده , , Takeshi and Shoji، نويسنده , , Mitsuru، نويسنده ,
Abstract :
Steroids with A/B cis-decalin moiety and various bioactivities have attracted many synthetic chemists as target molecules and development of efficient methodology providing cis-decalins has been desired. A stereoselective domino cyclization via Mn(OAc)3 and Cu(OTf)2-mediated radical reaction was found to be effective to construct cis-decalin framework.
Keywords :
cis-decalin , radical cyclization , Domino reaction , stereoselective synthesis , Steriod
