Title of article :
Chemo and diastereoselective conjugate addition of Grignard reagents on parthenin, a bioactive natural sesquiterpene lactone
Author/Authors :
Kashanna، نويسنده , , Jajula and Jangili، نويسنده , , Paramesh and Kumar، نويسنده , , Rathod Aravind and Rao، نويسنده , , Bethapudirr Rama، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The conjugate addition on a natural bioactive pseudoguaianolide sesquiterpene lactone parthenin with various Grignard reagents leads to 13-C alkylated products chemo and diastereoselectively in fair overall yields. Compared with other Grignard reagents vinyl and smaller straight chain alkyl Grignard reagents gave better yields.
Keywords :
Mono nucleophilic addition , Grignard reagents , Chiral products , diastereoselectivity , Parthenin analogues
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
