Title of article
A practical one-pot procedure for the synthesis of N–H isoquinolones
Author/Authors
Lu، نويسنده , , Shaonan and Lin، نويسنده , , Yingfu and Zhong، نويسنده , , Hongban and Zhao، نويسنده , , Kang and Huang، نويسنده , , Jianhui، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
2001
To page
2005
Abstract
A practical one-pot procedure for the preparation of N–H isoquinolones has been developed. This 2-step process via C–H activation of N-alkoxyl benzamides and NaH-mediated dealkoxylation reaction has been demonstrated to be a high yielding alternative methodology for the efficient synthesis of a wide range of representative N–H isoquiolones. In addition, the experimental precedent supported mechanism of the dealkoxylation reaction was also proposed.
Keywords
Isoquinolone , C–H activation , Organometallics , Pd-catalysis , N–O bond cleavage
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884193
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