Author/Authors :
Rambabu، نويسنده , , D. and Bhavani، نويسنده , , S. and Nalivela، نويسنده , , Kumara Swamy and Mukherjee، نويسنده , , Soumita and Rao، نويسنده , , M.V. Basaveswara and Pal، نويسنده , , Manojit، نويسنده ,
Abstract :
10% Pd/C in combination with CuI, PPh3, and Et3N has been identified as an effective catalyst system for the coupling of (Z)-3-iodoacrylic acid with terminal alkynes in 1,4-dioxane leading to the one-pot synthesis of γ-ylidene butenolides. The methodology showed remarkable regio- and stereoselectivity as only the five-membered lactone ring products were formed with an exocyclic double bond possessing Z-geometry.
Keywords :
Pd/C , butenolides , cyclization , Coupling
