• Title of article

    CaF2 catalyzed SN2 type chlorodehydroxylation of chiral secondary alcohols with thionyl chloride: a practical and convenient approach for the preparation of optically active chloroalkanes

  • Author/Authors

    Zhang، نويسنده , , Junjie and Wang، نويسنده , , Huanxia and Ma، نويسنده , , Yun and Wang، نويسنده , , Youming and Zhou، نويسنده , , Zhenghong and Tang، نويسنده , , Chuchi Tang، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2013
  • Pages
    3
  • From page
    2261
  • To page
    2263
  • Abstract
    A CaF2 catalyzed chlorodehydroxylation of chiral secondary alcohols with thionyl chloride has been developed. The chlorination reaction is effective for a wide range of alcohols, generating the corresponding chloroalkanes in good yield with high optical purity with inversion of the original configuration of the alcohol.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2013
  • Journal title
    Tetrahedron Letters
  • Record number

    1884306