Author/Authors :
Zhang، نويسنده , , Junjie and Wang، نويسنده , , Huanxia and Ma، نويسنده , , Yun and Wang، نويسنده , , Youming and Zhou، نويسنده , , Zhenghong and Tang، نويسنده , , Chuchi Tang، نويسنده ,
Abstract :
A CaF2 catalyzed chlorodehydroxylation of chiral secondary alcohols with thionyl chloride has been developed. The chlorination reaction is effective for a wide range of alcohols, generating the corresponding chloroalkanes in good yield with high optical purity with inversion of the original configuration of the alcohol.
