Enantioselective direct fluorination and chlorination of cyclic β-ketoesters mediated by phase-transfer catalysts
Author/Authors :
Luo، نويسنده , , Jie and Wu، نويسنده , , Wenqin and Xu، نويسنده , , Li-Wen and Meng، نويسنده , , Yuezhong and Lu، نويسنده , , Yixin، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Pages :
4
From page :
2623
To page :
2626
Abstract :
A straightforward and practical method for the direct fluorination and chlorination of various β-ketoesters employing a phase-transfer catalyst is developed. The desired products with fluorine/chlorine-substituted quaternary chiral centers are prepared with good to excellent enantioselectivities.
