Title of article
Synthesis of 3-(1H-benzo[d]imidazol-1-yl)isoindolin-1-one derivatives promoted by EtOH–AcOH solvent system
Author/Authors
You، نويسنده , , Hanyun and Chen، نويسنده , , Fanglei and Lei، نويسنده , , Min and Hu، نويسنده , , Lihong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
2972
To page
2975
Abstract
A simple and efficient method for the synthesis of 3-(1H-benzo[d]imidazol-1-yl)isoindolin-1-one derivatives by a one-pot, three-component condensation reaction of phthalaldehydic acid, primary amine, and 2-mercaptobenzimidazole or 2-hydroxybenzimidazole is described. By using EtOH–AcOH (v/v, 15:1) as the solvent system, the reaction proceeds smoothly to give corresponding products in good yields.
Keywords
2-Mercaptobenzimidazole , Phthalaldehydic acid , Multi-component reactions (MCRs) , Isoindolin-1-one , green chemistry
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884603
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