Title of article :
Enantioselective bioreduction of ethyl 4,4,4-trihalide-3-oxobutanoate by Kluyveromyces marxianus
Author/Authors :
Oliveira، نويسنده , , Simone Santos de Sousa and Dias، نويسنده , , Luiza Rosلria Sousa and Barbosa، نويسنده , , Natane Cezario and Bello، نويسنده , , Murilo L. and Novaes، نويسنده , , Fلbio Jْnior Moreira and Ramos، نويسنده , , Maria da Conceiçمo Klaus V. and Aquino Neto، نويسنده , , Francisco Radler de and Fiaux، نويسنده , , Sorele Batista and Leite، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
Resting cells of Kluyveromyces marxianus were used in the bioreduction of ethyl 4,4,4-trifluoro-3-oxobutanoate and ethyl 4,4,4-trichloro-3-oxobutanoate with 81% and 4% yields and 29% and 73% enantiomeric excess, respectively. The differences observed were attributed to the tri-halide structures.
Keywords :
4 , 4-trifluoro-3-oxobutanoate , 4 , 4-trichloro-3-oxobutanoate , Bioreduction , Ethyl 4 , kluyveromyces marxianus , Ethyl 4
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
