Title of article
Chiral phosphoric acid catalyzed asymmetric hydrogenolysis of racemic 3-aryl-3-hydroxyisoindolin-1-ones
Author/Authors
Zhou، نويسنده , , Jian-Qing and Sheng، نويسنده , , Wei-Jian and Jia، نويسنده , , Jianhong and Ye، نويسنده , , Qing and Gao، نويسنده , , Jian-Rong and Jia، نويسنده , , Yi-Xia، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
3082
To page
3084
Abstract
The enantioselective hydrogenolysis of racemic 3-aryl-3-hydroxyisoindolin-1-ones catalyzed by BINOL-derived chiral phosphoric acid with benzothiazoline as the hydride source is described. The corresponding cyclic diaryl methylamines are obtained in good to excellent yields and up to 91% enantioselectivities.
Keywords
Chiral phosphoric acid , Hydrogenolysis , Imine reduction , Asymmetric organocatalysis
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884652
Link To Document